| Autor: |
Wistow G, Alligood J, Shinohara T, Somers R |
| Jazyk: |
angličtina |
| Zdroj: |
FEBS letters [FEBS Lett] 1983 Sep 19; Vol. 161 (2), pp. 221-4. |
| DOI: |
10.1016/0014-5793(83)81012-6 |
| Abstrakt: |
Uniquely among the soluble lens-specific proteins, gamma-crystallin is capable of binding the strongly chromophoric aldehyde retinal. A role for gamma-crystallin in protecting lens components from toxic aldehydes resulting from membrane oxidation is proposed and a molecular model of the probable interaction site is presented. The sequence of a tetrapeptide at this site is identical to that of the retinal binding site of bacteriorhodopsin. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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