| Autor: |
Shildt RA, Kennedy PS, Chen TT, Athens JW, O'Bryan RM, Balcerzak SP |
| Jazyk: |
angličtina |
| Zdroj: |
Cancer treatment reports [Cancer Treat Rep] 1983 Jan; Vol. 67 (1), pp. 77-9. |
| Abstrakt: |
The Southwest Oncology Group evaluated 51 patients with a histologic diagnosis of metastatic adenocarcinoma and an occult primary tumor. Even though all patients received an extensive diagnostic evaluation, only six (12%) primary sites were found. Thirty-six patients whose primary tumor sites remained occult were randomized to receive either 5-FU or combination chemotherapy (5-FU, doxorubicin, and cyclophosphamide [FAC]). There were no responses in either group. The median survival with 5-FU was 105 days and with FAC was 95 days. Toxicity with FAC was more common and more severe. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
|
