Eosinophilic fasciitis: a distinct clinical entity?

Autor: Naguwa SM, Robbins DL, Castles JJ
Jazyk: angličtina
Zdroj: The American journal of the medical sciences [Am J Med Sci] 1983 Sep-Oct; Vol. 286 (2), pp. 32-5.
DOI: 10.1097/00000441-198309000-00006
Abstrakt: Eosinophilic Fasciitis is a syndrome characterized by exertion related scleroderma-like skin changes, peripheral eosinophilia, hypergammaglobulinemia and diffuse faciitis. Controversy exists as to the precise classification of the syndrome, i.e., whether it is a distinct entity or a variant of scleroderma. We describe a patient with eosinophilic faciitis but with several unique features: 1) progressive skin changes unresponsive to corticosteroid therapy; 2) elevated anti-DNA antibodies; 3) hypocomplementemia; and 4) a followup biopsy showing sclerodermatoid skin changes. These features and others relating to the controversial aspects of classification of eosinophilic fasciitis are discussed.
Databáze: MEDLINE