| Autor: |
Naharro G, Dunn CY, Robbins KC |
| Jazyk: |
angličtina |
| Zdroj: |
Virology [Virology] 1983 Mar; Vol. 125 (2), pp. 502-7. |
| DOI: |
10.1016/0042-6822(83)90223-4 |
| Abstrakt: |
The Gardner-Rasheed strain of feline sarcoma virus (GR-FeSV), is a recent isolate of a naturally occurring cat sarcoma. The primary translational product of GR-FeSV (GR P70) was shown to be a phosphoprotein with associated tyrosine-specific protein kinase activity. The relationship between the GR-FeSV provirus and once genes of other transforming retroviruses known to code for tyrosine kinases was examined by molecular hybridization. Probes repesenting onc genes of Snyder-Theilen and McDonough strains of feline sarcoma virus, Rous sarcoma virus, and Abelson murine leukemia virus did not detectably hybridize integrated GR-FeSV. These findings suggest that GR-FeSV contains a distinct tyrosine kinase-coding onc gene. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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