| Autor: |
Iversen SA, Murphy PG, Leakey TE, Rydlewski A, Levy RD, Gertner D |
| Jazyk: |
angličtina |
| Zdroj: |
Human toxicology [Hum Toxicol] 1984 Dec; Vol. 3 (6), pp. 509-12. |
| DOI: |
10.1177/096032718400300606 |
| Abstrakt: |
A 58-year-old man with a history of alcoholic liver disease and chronic airflow obstruction presented with heart failure and acute bronchitis. Plasma methylxanthines were estimated as a guide to further theophylline therapy and serious caffeine accumulation was noted in the presence of a subtherapeutic concentration of theophylline. After 3 weeks on a caffeine-free diet theophylline and caffeine challenge tests were performed which demonstrated the ease with which caffeine could accumulate. The importance of caffeine accumulation during theophylline therapy is discussed. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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