| Autor: |
Depaolis AM, Britt TE, Holman AJ, McGonigle EJ, Kaplan G, Davies WC |
| Jazyk: |
angličtina |
| Zdroj: |
Journal of pharmaceutical sciences [J Pharm Sci] 1984 Nov; Vol. 73 (11), pp. 1650-1. |
| DOI: |
10.1002/jps.2600731143 |
| Abstrakt: |
A rapid and sensitive high-performance liquid chromatographic quantitation of meclocycline (I) in a cream formulation is described. The acidified methanolic extract of the sample was diluted with mobile phase and analyzed on a reverse-phase column by using a mobile phase consisting of EDTA buffer (pH 6.6)-tetrahydrofuran (85:15 v/v). The method gave linear, quantitative, and reproducible results with a detection limit of 0.4 ppm for meclocycline. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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