Procainamide-induced agranulocytosis.

Autor: Reidy TJ, Upshaw JD Jr
Jazyk: angličtina
Zdroj: Southern medical journal [South Med J] 1984 Dec; Vol. 77 (12), pp. 1582-4.
DOI: 10.1097/00007611-198412000-00027
Abstrakt: We have described six new patients accounting for seven episodes of agranulocytosis due to procainamide. Six episodes involved the slow-release oral preparation. With continued use of this convenient antiarrhythmic agent, it is important that physicians be alert to the possibility of agranulocytosis in febrile patients receiving procainamide. If agranulocytosis occurs, procainamide should be discontinued promptly and the fever should be treated aggressively with combination broad spectrum antibiotics.
Databáze: MEDLINE