| Autor: |
Kagan VE, Savov VM, Serbinova EA |
| Jazyk: |
angličtina |
| Zdroj: |
Acta physiologica et pharmacologica Bulgarica [Acta Physiol Pharmacol Bulg] 1984; Vol. 10 (2), pp. 73-81. |
| Abstrakt: |
It was demonstrated that endogenous lipid peroxidation (LPO) is an effective mechanism of disassembly of endoplasmic reticulum membranes and cytochrome P-450 (P-448) in the liver. The rate of cytochrome P-450 (P-448) degradation in vivo can be regulated by free radical scavengers. The constitutive forms of cytochrome P-450 (P-448) are less sensitive to LPO induced in vivo or in vitro than the inducible ones. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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