| Autor: |
Aslamova LI, Blium IaB, Tsudzevich BA, Kucherenko NE |
| Jazyk: |
ruština |
| Zdroj: |
Radiobiologiia [Radiobiologiia] 1984 Jul-Aug; Vol. 24 (4), pp. 445-50. |
| Abstrakt: |
Phosphorylation and synthesis of histones and nonhistone proteins were studied after the inhibition of translation by sublethal cycloheximide doses. Activation of the chromatin protein phosphorylation was noted: (1) at the stage of recovery and stimulation of the protein synthesis (18-24 h), and (2) at the stage of activation of the replicative DNA synthesis (30-60 h). Phosphorylation and synthesis of the chromatin proteins depended upon the individual or combined effect of X-radiation and serotonin. The authors discuss the possible role of the chromatin protein phosphorylation in the response of the nuclear apparatus to the effect of radiation and serotonin the latter being used as a radioprotective agent. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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