Autor: |
Kisner DL, Mehta P, Paget GE, Von Hoff DD |
Jazyk: |
angličtina |
Zdroj: |
Investigational new drugs [Invest New Drugs] 1984; Vol. 2 (1), pp. 55-8. |
DOI: |
10.1007/BF00173787 |
Abstrakt: |
The antitumor activity of Carbetimer was tested against 171 patient's tumors in a human tumor cloning system. Sixty-seven tumor specimens had adequate growth to be considered evaluable. In 21 specimens survival of tumor colony forming units was less than or equal to 50% that in control plates. Antitumor effect was most impressive in carcinomas of the breast, ovary, and lung. This information will be useful in planning disease oriented Phase II trials. |
Databáze: |
MEDLINE |
Externí odkaz: |
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