| Autor: |
Dement'eva NP, Koroleva LA |
| Jazyk: |
ruština |
| Zdroj: |
Voprosy onkologii [Vopr Onkol] 1984; Vol. 30 (7), pp. 51-4. |
| Abstrakt: |
Thirty cases of disseminated skin melanoma were treated with nitrosomethylurea which was given in 2-3 week courses (10 mg/kg twice a week each) at 1-2 month intervals. Complete response with a recurrence-free period of 6 months to over 3 years was registered in 3 patients (10%). A decrease in tumor size by more than 50% within 5-12 months was secured in 6 patients (20%). The responders survived longer than those in whom the treatment had failed. Side-effects were moderate and reversible. Nitrosomethylurea should be widely used in treatment of skin melanoma. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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