Detection of hepatitis B surface antigen subtype adr in an epidemic of papular acrodermatitis of childhood (Gianotti's disease).

Autor: Kanzaki S, Kanda S, Terada K, Nohno S, Kumano K, Narahara K, Hayashi H, Kimoto H
Jazyk: angličtina
Zdroj: Acta medica Okayama [Acta Med Okayama] 1981 Dec; Vol. 35 (6), pp. 407-10.
DOI: 10.18926/AMO/31260
Abstrakt: Papular acrodermatitis of childhood (PAC) has recently been reported to be associated with hepatitis B surface antigen (HBsAg) subtype ayw. Between September, 1978, and June, 1979, we saw 14 patients with PAC in a small epidemic occurring in Iwakuni City, Japan. HBsAg was detected in sera from all patients. Subtyping of HBsAg in 11 patients showed that 8 had a determinant adr and 3 had no detectable determinant because of low antigen titers. The result suggests that factors other than the specific HBsAg subtype contribute to the development of PAC.
Databáze: MEDLINE