Synergistic antileukemic activity of combinations of two nitrosoureas.

Autor: Wheeler GP, Schabel FM Jr, Trader MW
Jazyk: angličtina
Zdroj: Cancer treatment reports [Cancer Treat Rep] 1981 Jul-Aug; Vol. 65 (7-8), pp. 591-9.
Abstrakt: A rationale based on known chemical, biochemical, and biologic properties of nitrosoureas led to the testing of combinations of CCNU with chlorozotocin for in vivo activity against L1210 leukemia. Several combinations yielded synergistic antileukemic activity.
Databáze: MEDLINE