Successful rat pancreatic islet allotransplantation without recipient immunosuppression.

Autor: Tucker K, Suzuki M, Waldeck NJ, Jones G, Charles MA
Jazyk: angličtina
Zdroj: Cellular immunology [Cell Immunol] 1983 Jul 15; Vol. 79 (2), pp. 403-6.
DOI: 10.1016/0008-8749(83)90083-7
Abstrakt: Pancreatic islets from Wistar Furth (RT1u) rats are rejected by 5 days after transplantation into the liver of the diabetic Lewis (RT11) rat. Pretreatment of Wistar Furth islets by culture for 7-10 days in 95% O2 5% CO2 reduces immunogenicity permitting successful allotransplantation as defined by normal blood and 24-hr urinary glucose values.
Databáze: MEDLINE