| Autor: |
Ponassi A, Morra L, Caristo G, Parodi GB, Biassoni P, Sacchetti C |
| Jazyk: |
angličtina |
| Zdroj: |
Acta haematologica [Acta Haematol] 1983; Vol. 70 (1), pp. 19-23. |
| DOI: |
10.1159/000206684 |
| Abstrakt: |
Total and differential leucocyte countings, mobilization of the marrow granulocyte reserve with hydrocortisone and growth of blood colony-forming cells (CFU-C) in agar culture have been evaluated in 17 patients with Graves' disease before therapy. Moreover, the myeloid differentiation of blood CFU-C in liquid culture has been studied in 4 patients. Neutropenia was found in only 1 patient (5.9%), while the marrow granulocyte reserve was reduced in 7 out of 15 patients (46.7%). Blood concentration of CFU-C and myeloid differentiation in liquid culture were normal in all patients studied. These data show an abnormal granulopoiesis in a high percentage of patients with untreated Graves' disease. The mechanisms accounting for the reduction of the marrow granulocyte reserve in patients with Graves' disease are discussed. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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