| Autor: |
Raap J, Kerling KE, Vreeman HJ, Visser S |
| Jazyk: |
angličtina |
| Zdroj: |
Archives of biochemistry and biophysics [Arch Biochem Biophys] 1983 Feb 15; Vol. 221 (1), pp. 117-24. |
| DOI: |
10.1016/0003-9861(83)90127-3 |
| Abstrakt: |
Circular dichroism spectra of a series of synthetic, kappa-casein-related oligopeptide substrates for chymosin in water and in surfactant solution were determined. The results show that there is a good correlation between the beta-structure forming potential of these peptides as found by using structure-predictive methods and the conformation in dilute sodium dodecyl sulfate solutions. The results support earlier suggestions concerning enzyme-substrate interaction which were made on the basis of X-ray analysis of acid proteinases. A predicted secondary structure of the whole kappa-casein molecule obtained by using a combination of three methods is also presented. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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