Autor:	Verkhogliad IN, Dragan AI, Vinogradova RP, Kucherenko NE
Jazyk:	ruština
Zdroj:	Radiobiologiia [Radiobiologiia] 1984 Nov-Dec; Vol. 24 (6), pp. 748-52.
Abstrakt:	The parameters of proper fluorescence of lysil-tRNA-synthetase from rat liver were determined in normal conditions and after X-irradiation. Irradiation of animals with a minimal absolutely lethal dose (0.21 C/kg) caused conformational transformations of the protein molecule accompanied by a change in the microenvironment of the chromophores: 60 min after irradiation it became less polar and after 24 h more polar than normal. The changes in the conformational status of the enzyme molecules after irradiation were connected with a change in the specific activity of lysil-tRNA-synthetase.
Databáze:	MEDLINE
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