Response of monkeys to porcine zona pellucida as detected by a solid-phase radioimmunoassay.

Autor: Gulyas BJ, Yuan LC, Gwatkin RB, Schmell ED
Jazyk: angličtina
Zdroj: Journal of medical primatology [J Med Primatol] 1983; Vol. 12 (6), pp. 331-42.
Abstrakt: The immunological response of cynomolgus monkeys (Macaca fascicularis) to immunization was evaluated utilizing collagenase-isolated pig zona pellucida. Six weeks after initial immunization a high serum titer of antibody was exhibited. Serum antibody titers demonstrated a noticeable decline 5 months after booster injections were discontinued. The assay method used is rapid and is capable of detecting antibody in serum dilutions of 1:78,000, as compared to 1:125,000 with the indirect fluorescence assay.
Databáze: MEDLINE