Cure of intractable watery diarrhoea by excision of a vipoma.
Autor: | Modlin IM, Bloom SR, Barnes A, Welbourn RB |
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Jazyk: | angličtina |
Zdroj: | The British journal of surgery [Br J Surg] 1978 Apr; Vol. 65 (4), pp. 234-6. |
DOI: | 10.1002/bjs.1800650406 |
Abstrakt: | A 56-year-old man suffered unexplained watery diarrhoea for 5 years which ultimately produced quadraparesis due to serve potassium depletion. All investigations were negative until demonstration of elevated plasma vasoactive intestinal peptide (VIP) indicated the presence of a vipoma. Removal of the VIP-producing tumour tissue--an adrenal ganglioneuroma--resulted in complete cure. Plasma VIP measurement is thus a valuable diagnostic screen in such cases and can be used to predict prognosis and to guide further therapy. |
Databáze: | MEDLINE |
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