| Autor: |
Vesikari T, Ala-Laurila EL, Heikkinen A, Terho A, D'Hondt E, André FE |
| Jazyk: |
angličtina |
| Zdroj: |
American journal of diseases of children (1960) [Am J Dis Child] 1984 Sep; Vol. 138 (9), pp. 843-7. |
| DOI: |
10.1001/archpedi.1984.02140470043013 |
| Abstrakt: |
Trivalent measles-mumps-rubella virus vaccines, containing either Schwarz (two dosage levels), Urabe Am 9, and RA 27/3 strains or Moraten, Jeryl Lynn, and RA 27/3 strains, were evaluated in 174 children aged 14 to 24 months. Each of the three vaccines induced a nearly 100% seroconversion for measles and mumps and a full 100% seroconversion for rubella. Close home monitoring disclosed a high incidence and a relatively constant pattern of vaccine-associated reactions, similar for all three vaccines. Febrile reactions of greater than or equal to 39 degrees C between days 5 and 12 after vaccination were more frequent among the recipients of "high"-dose Schwarz strain vaccine (35%) than among the recipients of corresponding "low"-dose vaccine (13%). The Schwarz-Urabe Am 9-RA 27/3 was equally immunogenic and, with a low dose of measles virus, no more reactogenic than the Moraten-Jeryl Lynn-RA 27/3 trivalent vaccine. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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