The isolation and characterization of an insulin-releasing tetrapeptide from urines of patients with lipoatrophic diabetes.

Autor: Reichelt KL, Johansen JH, Titlestad K, Edminson PD
Jazyk: angličtina
Zdroj: Biochemical and biophysical research communications [Biochem Biophys Res Commun] 1984 Jul 18; Vol. 122 (1), pp. 103-10.
DOI: 10.1016/0006-291x(84)90445-5
Abstrakt: The tetrapeptide pyroGlu-Glu-Asp-GlyOH and its gamma-amide have been isolated from the urines of lipodystrophic patients with insulin-resistant diabetes. Both peptides induce insulin release only at high blood glucose levels.
Databáze: MEDLINE