| Autor: |
Mkrtchian LN, Ter-Pogosian ZR, Sarkisian OM, Gevorkian RA, Movsesian EA |
| Jazyk: |
ruština |
| Zdroj: |
Voprosy onkologii [Vopr Onkol] 1983; Vol. 29 (8), pp. 7-11. |
| Abstrakt: |
The study established an immunomodulating effect of preparations of human leukocytic interferon in spontaneous rosette-formation test (E--RFC) and leukocyte adherence inhibition reaction (LAI) which takes place both in healthy donors and patients with cervical carcinoma. In E--RFC test, administration of interferon preparations caused the E-rosette forming cell fraction to increase in donors. A similar but much lower effect was observed in the patient group. The effect of interferon produced by patients leukocytes was low. In LAI test, interferon treatment eliminated tumor antigen-induced inhibition in cases of cell-mediated immunity. However, it failed to materially affect the fraction of adhering cells in cases of negative reaction. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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