Autor: |
Neuman TE, Laasberg TA, Kiarner IuK |
Jazyk: |
ruština |
Zdroj: |
Ontogenez [Ontogenez] 1984 Jan-Feb; Vol. 15 (1), pp. 88-91. |
Abstrakt: |
The isolated Hensen's nodes of chick embryos (stage 4 after Hamburger and Hamilton) were cultivated in organotypic cultures after the treatment with 0.5 mM solutions of cAMP and cGMP. Both the control and treated explants were characterized by a wide variability of differentiation of various tissue rudiments. cGMP inhibited reliably the differentiation of notochord. At the ultrastructural level the control and cAMP-treated cultures were characterized by an increased autophagia whereas the treatment with cGMP inhibited the yolk utilization and resulted in the appearance of vast regions of partial necrosis. |
Databáze: |
MEDLINE |
Externí odkaz: |
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