[Beta-adrenergic mechanism of the radio-protective effect of isoproterenol in a mammalian cell culture].
| Autor: | Chirkov IuIu, Babiĭ NI, Sobolev AS |
|---|---|
| Jazyk: | ruština |
| Zdroj: | Radiobiologiia [Radiobiologiia] 1983 Nov-Dec; Vol. 23 (6), pp. 819-22. |
| Abstrakt: | A specific beta-agonist, isoproterenol, increased the intracellular content of cyclic AMP and decreased the radiosensitivity of Chinese hamster fibroblasts. Beta-antagonist, propranolol, blocked the manifestation of the effect of isoproterenol. Isoproterenol did not affect either the intracellular level of cyclic AMP or the radiosensitivity of B-82 cells which had no beta-adrenoreceptors. |
| Databáze: | MEDLINE |
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