| Autor: |
Williams M, Risley EA, Robinson JL |
| Jazyk: |
angličtina |
| Zdroj: |
Neuroscience letters [Neurosci Lett] 1983 Jan 31; Vol. 35 (1), pp. 47-51. |
| DOI: |
10.1016/0304-3940(83)90525-6 |
| Abstrakt: |
Antidepressants and electroconvulsive shock therapy (ECS) have been reported to alter adenosine-sensitive adenylate cyclase responses in rat brain, suggesting an involvement of the purine in the mechanisms by which antidepressants and antidepressant therapy produce their clinical effects. Chronic (14-21 days, 10 mg/kg/day by Alzet minipump) treatment with desmethylimipramine (DMI) and mianserin, while producing changes in beta-adrenoceptor (DMI) and serotonin-2 (DMI and mianserin) radioligand binding similar to those reported in the literature, has no effect on adenosine A-1 radioligand binding. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
|
