| Autor: |
Garte SJ, Fennikoh KB, Belman S |
| Jazyk: |
angličtina |
| Zdroj: |
Mechanisms of ageing and development [Mech Ageing Dev] 1982 Mar; Vol. 18 (3), pp. 209-14. |
| DOI: |
10.1016/0047-6374(82)90110-5 |
| Abstrakt: |
The beta-adrenergic hormone responsiveness of mouse epidermis exhibited an age-dependent decrease. The 3-4-fold loss of response to isoproterenol was seen between 3 and 6 months of age, and the response remained at a depressed level through 18 months of age. No differences were seen between either the number or binding affinities of epidermal beta-receptors in 2- and 12-month-old animals. The skin tumor promoter, phorbol myristate acetate, inhibited the beta-adrenergic response independently of age. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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