Primary structure of Escherichia coli RNA polymerase nucleotide substitution in the beta subunit gene of the rifampicin resistant rpoB255 mutant.

Autor: Ovchinnikov YuA, Monastyrskaya GS, Gubanov VV, Lipkin VM, Sverdlov ED, Kiver IF, Bass IA, Mindlin SZ, Danilevskaya ON, Khesin RB
Jazyk: angličtina
Zdroj: Molecular & general genetics : MGG [Mol Gen Genet] 1981; Vol. 184 (3), pp. 536-8.
DOI: 10.1007/BF00352535
Abstrakt: The transducing phage lambda dsupM814 and the plasmid pIB1830 containing the wild-type rpoB gene have been constructed and the primary structure of the gene's central fragment has been established. In contrast with the wild-type, the gene of the rpoB255 mutant, whose primary structure has been published, was found to contain an A.T. leads to T.A. transversion entailing the substitution of a valine residue for the aspartic acid residue (516) of the wild-type beta subunit.
Databáze: MEDLINE