| Autor: |
Grigor'ev PA, Markevich NI |
| Jazyk: |
ruština |
| Zdroj: |
Biofizika [Biofizika] 1981 Nov-Dec; Vol. 26 (6), pp. 999-1003. |
| Abstrakt: |
Experiments on selective properties of the flavomycoin channels in a lipid bilayer in the solution of KCl show that the permeability ratio PCl/PK decreased with KCl concentration. A mathematical model of ion transport is developed which provides a quantitative description of the observed nonmonotonic dependence of transmembrane potential at a zero current on the concentration of KCl. An increase in PK relative to PCl is due to the difference in location of the binding sites of K+ and Cl- in a channel. The binding sites of Cl- are closer to the channel mouth as compared with those of K+. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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