| Autor: |
Paaren HE, Fivizzani MA, Schnoes HK, DeLuca HF |
| Jazyk: |
angličtina |
| Zdroj: |
Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 1981 Oct; Vol. 78 (10), pp. 6173-5. |
| DOI: |
10.1073/pnas.78.10.6173 |
| Abstrakt: |
The three-step conversion of vitamin D analogs to 6-oxo-3,5-cyclovitamin D derivatives followed by reduction with a tritide or deuteride reagent and subsequent cycloreversion gives 6-tritio(deutero)vitamin D derivatives and corresponding 5,6-trans-analogs. The method is general and affords the 6-labeled-vitamin D analogs in approximately 20% overall yield. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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