| Autor: |
Tedder RS, Mortimer PP, Lord RB |
| Jazyk: |
angličtina |
| Zdroj: |
Journal of medical virology [J Med Virol] 1981; Vol. 8 (2), pp. 89-101. |
| DOI: |
10.1002/jmv.1890080203 |
| Abstrakt: |
A simple, sensitive, and specific competitive solid phase immunoassay for antibody to varicella-zoster virus (anti-VZV) is described. The assay uses reagents that can easily be prepared and is sparing of viral antigen. Using a solid phase coated with sheep IgG from a serum raised against human mu-Fc, the same reagents will accurately detect anti-VZV IgM. The competitive assay divided sera from children from adults into immune and nonimmune groups that closely correlated with a history of previous VZV illness. It was not affected by the presence or absence of antibody to other herpes viruses. The IgM antibody capture assay demonstrated the presence of anti-VZV IgM in sera from patients with both varicella and zoster and gave negative results in patients with infections unrelated to VZV and in healthy blood donors. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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