Autor: |
De Montis GM, Olianas MC, Mulas G, Lloyd KG, Tagliamonte A |
Jazyk: |
angličtina |
Zdroj: |
Neuroscience letters [Neurosci Lett] 1981 May 29; Vol. 23 (3), pp. 257-61. |
DOI: |
10.1016/0304-3940(81)90007-0 |
Abstrakt: |
The perikarya of the dopaminergic and non-dopaminergic neurons contained in the substantia nigra were selectively destroyed by a proper, local injection of 6-hydroxydopamine or kainic acid, respectively. Both lesions resulted in a marked decrease of the nigral GABA-binding sites. The effect of 6-hydroxydopamine was restricted to the high affinity receptors, while kainic acid specifically decreased the low affinity ones. |
Databáze: |
MEDLINE |
Externí odkaz: |
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