Inhibitory effects of an aromatic retinoid (Ro 10-9359) on viral tumorigenesis.

Autor: Frankel JW, Horton EJ, Winters AL, Samis HV, Ito Y
Jazyk: angličtina
Zdroj: Intervirology [Intervirology] 1980; Vol. 14 (5-6), pp. 321-5.
DOI: 10.1159/000149203
Abstrakt: Prophylactic treatment of hamsters and chickens with an aromatic retinoid (Ro 10-9359) inhibited Rous sarcoma virus (RSV) tumorigenesis. Retinoid administration to chickens with RSV-induced tumors resulted in tumor regression and/or confinement to the primary site. The retinoid also exerted a therapeutic effect on Shope virus papilloma development in the skin of rabbits.
Databáze: MEDLINE