| Autor: |
Stein DC, Kopec LK, Yasbin RE, Young FE |
| Jazyk: |
angličtina |
| Zdroj: |
Applied and environmental microbiology [Appl Environ Microbiol] 1984 Aug; Vol. 48 (2), pp. 280-4. |
| DOI: |
10.1128/aem.48.2.280-284.1984 |
| Abstrakt: |
A Bacillus subtilis strain, DSM704, was characterized by genetic means, and its production of a human intestinal sucrase inhibitor, 1-deoxynojirimycin, was described. Synthesis of this compound is detected concomitant with the detection of heat-resistant spores. The amount of 1-deoxynojirimycin produced is highly dependent on the carbon source, with growth on substrates metabolized via glycolysis giving the greatest amount of production (up to 1 mg/ml). 1-Deoxynojirimycin appears to be nonmetabolizable by the producing strain in that it cannot serve as a sole carbon or nitrogen source. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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