Autor: |
Targum SD, Wheadon DE, Chastek CT, McCabe WJ, Advani MT |
Jazyk: |
angličtina |
Zdroj: |
Journal of affective disorders [J Affect Disord] 1982 Dec; Vol. 4 (4), pp. 347-53. |
DOI: |
10.1016/0165-0327(82)90030-1 |
Abstrakt: |
Hypothalamic-pituitary-adrenal (HPA) axis function was examined in 28 hospitalized, withdrawing alcoholic patients. Fourteen patients met DSM-III criteria for Major Depressive Disorder. Elevated 8 a.m. basal cortisols were noted in 7 depressed alcoholic patients (50%) and no non-depressed alcoholics (P less than 0.01). Escape from dexamethasone suppression was noted in 9 depressed alcoholics (64%) and no non-depressed alcoholics (P less than 0.005). The measurement of HPA axis function may be a useful marker for endogenous depression in an alcoholic population. |
Databáze: |
MEDLINE |
Externí odkaz: |
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