[The effect of exogenous RNA and their fragments on yeast beta-galactosidase activity].

Autor: Likhacheva LI, Kirillova VS, Kordium VA
Jazyk: ruština
Zdroj: Ukrainskii biokhimicheskii zhurnal (1978) [Ukr Biokhim Zh (1978)] 1984 Jul-Aug; Vol. 56 (4), pp. 384-90.
Abstrakt: It is shown that a degradation level of exogenic high-polymeric RNA does not change their stimulating effect on beta-galactosidase synthesis in yeast protoplasts. Nucleoside monophosphates are a product of RNA degradation which promotes an increase in the beta-galactosidase activity. The exogenic RNA is established to act at the transcription level. RNA and its degradation products stimulate the beta-galactosidase synthesis without any effect on the intensity of the total RNA and protein synthesis in the yeast protoplasts. All mentioned permitted a conclusion that products of RNA decay participate in the regulation of the beta-galactosidase synthesis of yeast. A possible mechanism of their action is under discussion.
Databáze: MEDLINE