| Autor: |
Liwnicz BH, Liwnicz RG, Huff JS, McBride BH, Tew JM Jr |
| Jazyk: |
angličtina |
| Zdroj: |
Neurosurgery [Neurosurgery] 1984 Aug; Vol. 15 (2), pp. 246-51. |
| DOI: |
10.1227/00006123-198408000-00017 |
| Abstrakt: |
We describe a case of a granular cell tumor (GCT) of the suprasellar region with an 11-year history in a 26-year-old woman. The computed tomographic scan showed a midline, contrast-enhancing, noncalcified mass. The biopsy was diagnosed as GCT. The tumor was treated with radiation therapy. At necropsy, a large, homogeneous GCT surrounded by gliosis was found. The tumor cells were filled with granules positive for periodic acid-Schiff, diastase-resistant. The cells did not contain glial fibrillary acidic protein or S-100 protein. Electron microscopy showed tumor cells filled with innumerable lysosomal structures. No intermediate filament was found within the cytoplasm. The tumor cells were not surrounded by a basement membrane. Based on this study and on our review of the literature, the suggestion that GCT has a multicellular origin is upheld. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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