| Autor: |
Friedlander ML, Atkinson K, Coppleson JV, Elliot P, Green D, Houghton R, Solomon HJ, Russell P, Tattersall MH |
| Jazyk: |
angličtina |
| Zdroj: |
Gynecologic oncology [Gynecol Oncol] 1984 Sep; Vol. 19 (1), pp. 1-7. |
| DOI: |
10.1016/0090-8258(84)90150-1 |
| Abstrakt: |
Chemotherapy has been traditionally reserved as a last-time treatment for cervical cancer patients and in this setting long-term remissions are unusual. Platinum-based combination chemotherapy has been associated with high tumor response rates in patients with advanced and metastatic cervical tumors and past experience encouraged evaluation of chemotherapy as a first-line treatment in patients with locally advanced tumors where there is a high likelihood of relapse with local treatment. Thirty patients were treated initially with three courses of cis-platinum, vinblastine, and bleomycin with an overall response rate of 67%, and then had either radiotherapy or surgical resection. The initial results have been encouraging and the integration of chemotherapy into the management of locally advanced cervical cancer warrants further investigation. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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