GDPmannose dehydrogenase and biosynthesis of alginate-like polysaccharide in a mucoid strain of Pseudomonas aeruginosa.

Autor: Pugashetti BK, Vadas L, Prihar HS, Feingold DS
Jazyk: angličtina
Zdroj: Journal of bacteriology [J Bacteriol] 1983 Feb; Vol. 153 (2), pp. 1107-10.
DOI: 10.1128/jb.153.2.1107-1110.1983
Abstrakt: GDPmannose dehydrogenase (EC 1.1.1.132) in a mucoid strain of Pseudomonas aeruginosa isolated from a patient with cystic fibrosis was identified by demonstrating the NAD-linked formation of GDPmannuronate from GDPmannose mediated by a cell extract of the organism. Nonmucoid mutant strains did not contain GDPmannose dehydrogenase, which suggests that the enzyme is involved in the biosynthesis of alginate-like polysaccharide by P. aeruginosa.
Databáze: MEDLINE