[Effect of vitamin E an actinomycin D on protein and RNA synthesis in rat liver].

Autor: Palivoda OM, Donchenko GV, Metal'nikova NP
Jazyk: ruština
Zdroj: Ukrainskii biokhimicheskii zhurnal (1978) [Ukr Biokhim Zh (1978)] 1981 Jan-Feb; Vol. 53 (1), pp. 67-71.
Abstrakt: In vitro experiments showed that RNA synthesis intensity in the rat liver with E-hypovitaminosis decreases considerably while the level of the labelled precursors incorporation into protein does not differ from the norm. Under conditions of E-hypovitaminosis the inhibitory effect of actinomycin D on the RNA synthesis is pronounced more clearly as compared to the norm. In the case of the E-hypovitaminous rate liver chyme preincubation with alpha-tocopherol there is no inhibitory effect of actinomycin D on the protein biosynthesis.
Databáze: MEDLINE