| Autor: |
Mross K, Mross B, Wolfrum DI, Kohlschütter A |
| Jazyk: |
angličtina |
| Zdroj: |
Research in experimental medicine. Zeitschrift fur die gesamte experimentelle Medizin einschliesslich experimenteller Chirurgie [Res Exp Med (Berl)] 1980; Vol. 177 (3), pp. 245-53. |
| DOI: |
10.1007/BF01851215 |
| Abstrakt: |
Lymphocytes from seven patients with malignancies, from seven patients with non-malignancies, and from five healthy persons were incubated with 125I-labeled MBP. Binding of MBP of lymphocytes was monitored from 0.5 to 20h. The binding ranged from 4 to 7% of the total MBP present and remained fairly constant during the first 4h of incubation. It dropped considerably at 20h. Mean percentages of MBP binding were lower in cancer patients than in persons without malignancies. After incubation, the supernates were examined by gel electrophoresis. The electrophoretic pattern was similar in comparing groups with different diagnoses. A considerable loss of MBP in the terminal supernatant (20h) was found. When tested in the electrophoretic mobility test (EM test) with stabilized erythrocytes, supernatant derived from cancer patients produced a somewhat higher mean slowing effect than did superntes from other patients and controls. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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