| Abstrakt: |
Virus-specific antigens in bone marrow cells of mice were investigated after inoculation of the animals with a set of live antiviral vaccines: poliovaccine type II, vaccinia, measles vaccine, and poliovaccine again sequentially at 14-day intervals, and after individual use of the same vaccines. The results indicate that the specific antigens of the viruses used for preparation of the vaccines under study could be detected in bone marrow cells of mice for quite long periods of time: vaccina virus and poliomyelitis vaccine virus antigens were detectable for 1--90 days, measles virus antigen for 1--60 days after immunization, predominantly in the cytoplasm of cells of the lymphoid series. |
