Synthesis of potential anticonvulsants: condensation of isatins with acetone and related ketones.

Autor: Popp FD, Parson R, Donigan BE
Jazyk: angličtina
Zdroj: Journal of pharmaceutical sciences [J Pharm Sci] 1980 Oct; Vol. 69 (10), pp. 1235-7.
DOI: 10.1002/jps.2600691035
Abstrakt: Substituted isatins were condensed with acetone and other ketones to give analogs of 3-hydroxy-3-acetonyloxindole. Some of these alcohols were dehydrated. Several compounds with anticonvulsant activity were obtained.
Databáze: MEDLINE