[Age and the role of certain mediators in the sensitivity of animals to hyperbaric oxygenation].

Autor: Bondarenko TI, Mendzheritskaia LG, Khodakova AA
Jazyk: ruština
Zdroj: Fiziologicheskii zhurnal SSSR imeni I. M. Sechenova [Fiziol Zh SSSR Im I M Sechenova] 1980 Aug; Vol. 66 (8), pp. 1251-5.
Abstrakt: Dynamics of biologically active brain peptides: N-acetyl-1-aspartat-1-glutamat (NAAG) and homocarnosine (gamma-aminobutyric-1-histidine), aminoacids and their derivatives GABA, histidine and histamine, in the blood of rats and rabbits of different age under hyperoxia was studied. Exposure of animals to 4 atm of oxygen considerably decreased NAA and NAAG contents in the brain of 21 and 30-day old rats and induced the 85% and 47% decrease of homocarnosine and GABA contents respectively in the brain of 30-day old rabbits. Brain histidine and blood histamine contents increased in 14, 21 and 30-day old rabbits.
Databáze: MEDLINE