Sarcomas of the uterine corpus: prognostic factors and treatment.

Autor: Shimm DS, Bell DA, Fuller AF, Bowling MC, Orlow EL, Munzenrider JE, Nelson JH Jr, Ingersoll FM, Nikrui N, Donovan J
Jazyk: angličtina
Zdroj: Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology [Radiother Oncol] 1984 Oct; Vol. 2 (3), pp. 201-7.
DOI: 10.1016/s0167-8140(84)80060-2
Abstrakt: Twenty-eight patients with sarcomas of the uterine corpus were followed at least 22 months or until death. All underwent laparotomy, eleven had radiation therapy, and six had chemotherapy. Three year actuarial survival was 24%, and three year actuarial local control was 36%. Multivariate analysis demonstrated that, as with sarcomas at other sites, the most important factors influencing survival were grade (P = 0.020) and stage (P = 0.022). For local control, multivariate analysis indicated the most important factors to be stage (P = 0.001) and radiation TDF (P = 0.01). Of 21 failures, 16 involved the pelvis, seven involved the upper abdomen, and 11 involved distant sites. The importance of both local and distant disease control is emphasized.
Databáze: MEDLINE