[Antitumor action of new 2,4-diethyleneimino-6-amino-sym.-triazina derivatives].

Autor: Maliugina LL, Pol'kina RI, Kraĭz BO, Remizov AL
Jazyk: ruština
Zdroj: Voprosy onkologii [Vopr Onkol] 1977; Vol. 23 (12), pp. 70-5.
Abstrakt: In experiments of mice and rats with transplantable tumors (sarcoma 37, sarcoma 45, ascites Ehrlich tumor, etc) the authors studied the antitumor activity of a number of new water-soluble derivatives of 2,4-diethylenimino-6-amino-sym.-triazine differing only in the substituting radical associated with sym.-triazine cycle. All substances under study showed marked antitumor activity. The effect of the structure of the compounds concerned and their physico-chemical properties for antitumor activity are discussed.
Databáze: MEDLINE