Toxin from skin of frogs of the genus Atelopus: differentiation from Dendrobatid toxins.

Autor: Fuhrman FA, Fuhrman GJ, Mosher HS
Jazyk: angličtina
Zdroj: Science (New York, N.Y.) [Science] 1969 Sep 26; Vol. 165 (3900), pp. 1376-7.
DOI: 10.1126/science.165.3900.1376
Abstrakt: A potent, dialyzable toxin (atelopidtoxin) occurs in the skin of frogs of the genus Atelopus. A concentrate of atelopidtoxin from Atelopus zeteki has an LD(50) in mice of 16 micrograms per kilogram. It differs from batrachotoxin, tetrodotoxin, and saxitoxin, the only known nonprotein substances of greater toxicity, as well as from all toxins previously isolated from amphibia.
Databáze: MEDLINE