| Autor: |
Maynard JE, Barrett DH, Murphy BL, Bradley DW, Berquist KR, Bender TR |
| Jazyk: |
angličtina |
| Zdroj: |
The Journal of infectious diseases [J Infect Dis] 1976 Mar; Vol. 133 (3), pp. 339-42. |
| DOI: |
10.1093/infdis/133.3.339 |
| Abstrakt: |
A study of the e determinant of hepatitis B surface antigen in an area of hepatitis B hyperendemicity revealed that the presence of e antigen or of antibody to e in the sera of individuals was specifically related to evidence of past or present infection with hepatitis B virus. Among asymptomatic long-term carriers of hepatitis B surface antigen, presence of the e antigen was associated with elevated levels of aspartate and alanine aminotransferases in serum; this observation suggested that the e antigen might be a marker for persisting hepatic dysfunction. Higher levels of DNA polymerase found in carriers of the surface antigen with e antigen suggested that these individuals might have a higher level of circulating Dane particles and thus, perhaps, a higher level of hepatitis B virus infectivity. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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