Homozygous Hb J Tongariki: evidence for only one alpha chain structural locus in Melanesians.

Asp) was found in a Kilenge village in New Britain. Heterozygotes had 45 to 50 percent of the Hb J component (determined by cellulose acetate electrophoresis). Two homozygotes for Hb J had no Hb A, suggesting that in this family only one Hbalpha structural locus is present. -->
Substance Nomenclature: 0 (Amino Acids)
0 (Hemoglobins, Abnormal)
0 (Peptides)
EC 3.4.21.1 (Chymotrypsin)
EC 3.4.21.4 (Trypsin)
Entry Date(s): Date Created: 19700710 Date Completed: 19700826 Latest Revision: 20190618
Update Code: 20240829
DOI: 10.1126/science.169.3941.194
PMID: 5427353
Autor: Abramson RK, Rucknagel DL, Shreffler DC, Saave JJ
Jazyk: angličtina
Zdroj: Science (New York, N.Y.) [Science] 1970 Jul 10; Vol. 169 (3941), pp. 194-6.
DOI: 10.1126/science.169.3941.194
Abstrakt: A high frequency of Hb J Tongariki (alpha 115 Ala --> Asp) was found in a Kilenge village in New Britain. Heterozygotes had 45 to 50 percent of the Hb J component (determined by cellulose acetate electrophoresis). Two homozygotes for Hb J had no Hb A, suggesting that in this family only one Hbalpha structural locus is present.
Databáze: MEDLINE
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