An explanation fro chloracne -- an industrial hazard.

Autor: Cunliffe WJ, Williams M, Edwards JC, Williams S, Holland KT, Roberts CD, Holmes RL, Williamson D, Palmer WC
Jazyk: angličtina
Zdroj: Acta dermato-venereologica [Acta Derm Venereol] 1975; Vol. 55 (3), pp. 211-4.
Abstrakt: Patients with chloracne were investigated and the results compared with data matched for age and site from patients with acne vulgaris. The ultrastructural appearances of pilo-sebaceous ducts in both groups were similar. The industrial group had significantly fewer C. acnes than the patients with ordinary acne. They also showed a significant increase in the surface lipid percentage composition of squalene, wax ester and cholesterol and this was associated with a significant decrease in the triglyceride free fatty acids and total triglyceride pool. We suggest that the acnegenic agent has produced its effect by modifying the metabolism of the pilo-sebaceous fluid.
Databáze: MEDLINE