Loss of the penicillinase plasmid after treatment of Staphylococcus aureus with sodium dodecyl sulfate.

Autor: Sonstein SA, Baldwin JN
Jazyk: angličtina
Zdroj: Journal of bacteriology [J Bacteriol] 1972 Jan; Vol. 109 (1), pp. 262-5.
DOI: 10.1128/jb.109.1.262-265.1972
Abstrakt: Two strains of Staphylococcus aureus (PC1 and 196E), when grown in medium containing 0.002% sodium dodecyl sulfate (SDS), showed from 96.1 to 100% loss of the ability to produce penicillinase. Resistance to cadmium and zinc was lost concomitantly with the ability to produce penicillinase. A comparison of the rate of curing by SDS with the curing effects exerted by elevated temperature and ethidium bromide suggested that SDS is a more effective plasmid curing agent for susceptible strains of S. aureus than methods in use at present.
Databáze: MEDLINE